KMID : 0614620200760030167
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Korean Journal of Gastroenterology 2020 Volume.76 No. 3 p.167 ~ p.170
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Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue
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Goh Hyun-Gil
Lee Yoo-Jin Kim Tae-Hyung
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Abstract
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Hepatic disorders with prominent cholestasis can be caused by a range of conditions, and anabolic androgenic steroids have been considered a cause of protracted cholestasis. A 29-year-old man who had taken an anabolic androgenic steroid analogue for 2 months visited the hospital complaining of jaundice and indigestion. After stopping the medication, the hyperbilirubinemia tended to decrease, but a transiently elevated aminotransferase level was observed. The endogenous testosterone level also decreased initially but recovered soon after. The liver function profiles were normalized after 2 months of conservative management. This case emphasizes that close drug history taking, including anabolic steroids, is important for identifying the cause of unexplained persistent jaundice.
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KEYWORD
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Jaundice, Anabolic agents, Steroids, Chemical and drug induced liver injury, Substance abuse, oral
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